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Mbocytes, and endothelial cells[43]. NS1 is a glycoprotein that is secreted by infected cells, heavily present in patient serum supernatants, lacks a membrane spanning motif, but is not, itself, present in the virus. NS1 is known to be a major immune target and high concentrations of antiNS1 antibodies have been found in severe disease in patient studies[44]. When cells are exposed to NS1 antibodi
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Mbocytes, and endothelial cells[43]. NS1 is a glycoprotein that is secreted by infected cells, heavily present in patient serum supernatants, lacks a membrane spanning motif, but is not, itself, present in the virus. NS1 is known to be a major immune target and high concentrations of antiNS1 antibodies have been found in severe disease in patient studies[44]. When cells are exposed to NS1 antibodi
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Ic methylation profile in CpG island methylator phenotype-negative distal colorectal cancers. Int J Cancer. 2010;127(9):2095-2105. doi: 10.1002/ijc.25225. PubMed 50. Worthley DL, Whitehall VL, Buttenshaw RL, Irahara N, Greco SA, Ramsnes I, Mallitt KA, Le Leu RK, Winter J, Hu Y, Ogino S, Young GP, Leggett BA. DNA methylation within the normal colorectal mucosa is associated with pathwayspecific pre
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Known to be "promiscuous" [109] with multiple binding partners. This promiscuity most likely is due to the multiple surfaces presented by the IDPs or the low energy requirement associated with their role in mineralization. Thus, it is not surprising that DMP1 can interact with cell membrane receptors (e.g. v3 integrin [122] to regulate signaling [123], FGF23 expression [66], bind to HA crystals so
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[21] has not been so encouraging . the antigenic/therapeutic protein in vivo[21] has not been so encouraging . the antigenic/therapeutic protein in vivo and to stimulate [25] potent specific humoral and cellular immune responses . RNA viral vectors, such as retrovirus and lentivirus, allow long-term expression of the transgene, while DNA viral vectors allow expression in episomal form. Viral
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This creamy smudge proof and waterproof formula will keep your lips looking on point all day and night. Find the mini lip brush located at the end of lip pencil along with the mini sharpener located on the other side. Shop Organza Lip Liner, Waterproof Lip Liner & Long Lasting Lip Liner online with confidence on House of the Rozetree!
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E to the change in entropy S, when an unstructured protein is bound and folded (transiently), is smaller than when a structured protein is bound ( G = H S). This concept may be debated, however, due to the relative order of the IDP vs. the dis-order of water upon IDP-partner binding in aqueous media. ii) An open structure gives an IDP the ability to bind to more than one partner and present dif
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Ldo F, Feghali-Bostwick CA, Varga J. The early growth response gene Egr2 (Alias Krox20) is a novel transcriptional target of transforming growth factor-beta that is up-regulated in systemic sclerosis and mediates profibrotic responses. Am J Pathol. 2011;178(5):2077-90. doi:10.1016/j.ajpath.2011.01. 035. PubMed PMID: 21514423; PMCID: PMC3081194. 27. Zaman G, Sunters A, Galea GL, Javaheri B, Saxon L